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Medicine

Alexander Fleming

Bacteriologist, Nobel Prize in Medicine 1945 for discovering penicillin

Born 1881 · Died 1955

Photo: Official photographer · Public domain

«One sometimes finds what one is not looking for.»

On the discovery of penicillin

Alexander Fleming noticed in 1928 that mould contaminating a forgotten culture dish had killed the bacteria around it, and identified the substance as penicillin. Antibiotics have since saved more lives than almost any other medical discovery.

Key achievements

  • Discovered penicillin in 1928, opening the antibiotic era
  • Nobel Prize in Medicine, 1945, with Florey and Chain
  • Warned of antibiotic resistance in his Nobel lecture

Universities

  • Imperial College LondonProfessor1901–1955

    London, South Kensington

    Trained and then worked for his whole career at St Mary's Hospital Medical School, now part of Imperial College London.

Facts

  • He made the discovery because he went on holiday and left the dish uncovered on a bench; he called it a lucky accident.
  • He could not produce penicillin in useful quantities, and it took Howard Florey and Ernst Chain at Oxford a decade to turn it into a medicine.
  • In his Nobel lecture he warned that careless use of penicillin would breed resistant bacteria, which is exactly what happened.

Photographs

Photographs come from Wikimedia Commons under free licences; the author and licence are shown on each image.

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